Objective: To study the dramatic response of levonorgestrel intrauterine system (LNG-IUS) Mirena for treatment of menorrhagia during its use as contraceptive.

Matera and methods: 30 women between 30 and 50 year with menorrhagia were included in a study over two year. Response was assessed monthly for first 4 month and then yearly for maximum 2 year.

Result; Mirena caused decrease in blood loss (MBL) in 16.7% of the patients at 4 month, 73.3% decrease in(MBL) by one year and 100% decrease by 2 years, and improved the mean Hb level in 100% of the patients after 2 years. Mirena has an effective in treatment of abnormal uterine bleeding and this made surgical intervention (Hysterectomy) is last choice.

Conclusion: LNG locally released on endometrium cavity is both a safe and reliable method of abnormal uterine bleeding treatment.