International Journal of Advanced Community Medicine
International Journal of Advanced Community Medicine
Vol. 3, Issue 1, Part D (2020)

Role of vitamin D supplementation for prevention and control of covid-19: A review article

Author(s): Dr. Harsh Vardhan Chawla, Dr. Nikita Singh, Dr. Arun Kumar and Dr. Sangeeta Bhattacharya
Abstract: COVID-19 is a novel respiratory disease which is caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), broke out in the end of winter season in 2019 in China and became a pandemic. Characteristically there is rapid local spread and very high systemic inflammatory response in the patients. Apart from high morbidity and mortality there has been tremendous social and financial impact in the entire world. A possibility exists that maintaining vitamin D sufficiency can increase the antimicrobial activity in the respiratory lining epithelium and inhibit the exaggerated cytokine inflammatory cascade thereby promoting repair of the respiratory epithelium. To date, no definitive treatment or preventive measure is available for COVID-19 other than symptomatic and supportive care.
By various mechanisms vitamin D is antimicrobial, immuno-modulatory and anti-inflammatory. These beneficial effects can be utilized as a measure for providing protection to the community at large in outbreak situations, when the population is susceptible. There is a high possibility that vitamin D supplementation in population at risk as well the cases of COVID-19 has a key role in prevention and control.
Hence, it is believed that oral vitamin D may be helpful in population at risk and cases to prevent and control COVID-19, during and prior to the development of active disease for boosting favorable immune response and relevant trials must be conducted to test this hypothesis.
Pages: 245-248  |  139 Views  95 Downloads
How to cite this article:
Dr. Harsh Vardhan Chawla, Dr. Nikita Singh, Dr. Arun Kumar and Dr. Sangeeta Bhattacharya. Role of vitamin D supplementation for prevention and control of covid-19: A review article. International Journal of Advanced Community Medicine. 2020; 3(1): 245-248. DOI: 10.33545/comed.2020.v3.i1d.158
International Journal of Advanced Community Medicine