Obesity plays a central role in the pathophysiology of both T2D and its macrovascular complications. The present study was conducted to assess correlation between obesity and glycated hemoglobin in type 2 diabetes patients.
Materials and Methods: 94 type II DM patients of both genders were included. Anthropometric measurements such as weight, height and BMI (kg/m2) was calculated. The waist circumference (WC) was measured. Patients were classified as Normal BMI: 18.0-22.9 kg/m2, Overweight: 23.0-24.9 kg/m2, Obesity: >25 kg/m2. Fasting plasma glucose was analyzed by glucose oxidase method and HbA1c by Latex agglutination inhibition assay.
Results: There were 23 normal, 30 overweight and 41 obese patients. The difference was significant (P<0.05). The mean FBG (mg/dl) was 151.4, 148.6 and 168.2, SBP (mm Hg) was 132.4, 128.4 and 130.6, DBP (mm Hg) was 86.2, 78.2 and 80.2, WC (cm) was 81.2, 94.5 and 100.6 and HbA1C (%) was 6.2, 8.1 and 8.9 in normal, overweight and obese patients respectively. The difference was significant (P<0.05).
Conclusion: Diabetic subjects had a higher prevalence of obesity. Dysglycemia was high in diabetic subjects with average BMI, overweight and obese.