Vol. 8, Issue 3, Part C (2025)

Background: Helicobacter pylori infection is a prevalent chronic bacterial infection associated with gastritis, peptic ulcers, and gastric cancer. Standard triple therapy (proton pump inhibitor + two antibiotics) is effective but challenged by antibiotic resistance. Natural remedies like Vinegar, particularly apple cider vinegar, have shown antimicrobial effects.
Aim of the study: To compare Vinegar as a supportive therapy to standard triple therapy regarding eradication, symptom improvement, adherence, and patient willingness to recommend treatment.
Results: No significant differences were observed between H. pylori and vinegar groups regarding age, gender, smoking status, treatment adherence, or symptom improvement (p>0.05). Completing the whole course was significantly associated with group allocation (P=0.03). Post-treatment test results showed a higher negative rate in the vinegar group (60% vs 20%, P=0.004). Moreover, more participants in the vinegar group were willing to recommend the treatment to others (60% vs 10%, P=0.001).
Conclusion: Vinegar treatment demonstrated superior effectiveness in H. pylori eradication compared to the standard therapy, reflected by higher negative test rates and greater willingness of participants to recommend it. Completion of the full treatment course remains crucial for optimal outcomes.